Molecular transduction in receptor-ligand systems by planar electromagnetic fields

نویسندگان

چکیده

Abstract The coupling of a ligand with molecular receptor induces signal that travels through the receptor, reaching internal domain and triggering response cascade. In previous work on T-cell receptors their foreign antigens, we observed presence planar patterns able to generate electromagnetic fields within proteins. These planes showed coherent (synchronized) behavior, replicating immediately in intracellular which occurred extracellular as was coupled. present study, examined this transduction - capacity penetrate deep inside molecule induce response. We verified synchronized behavior diverse receptor-ligand systems. To appreciate diversity, four biochemically different systems TCR-peptide, calcium pump-ADP, haemoglobin-oxygen, gp120-CD4 viral coupling. confirmation each these suggests proposed mechanism would occur all biochemical

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ژورنال

عنوان ژورنال: Brazilian Journal of Biology

سال: 2022

ISSN: ['1519-6984', '1678-4375']

DOI: https://doi.org/10.1590/1519-6984.232525